Scientist/Sr. Scientist, Computational Chemistry
General ProximityInduced proximity company
San Francisco, United StatesSenior
Y Combinator
Felicis
age1
Modi Ventures
Wilson Sonsini
Jim Dahl
Data & AI
About the role
TL;DR
Computational chemist to drive small-molecule drug discovery programs using modeling and AI tools.
- •General Proximity is seeking a computational chemist to pioneer the next generation of induced proximity medicines.
- •This role will drive small-molecule drug discovery programs by providing practical modeling support and applying modern computational workflows.
- •Key Responsibilities Provide hands-on computational chemistry support to small-molecule discovery programs.
- •Apply structure-based and ligand-based design approaches to guide compound design.
- •Use cheminformatics and AI-enabled tools to empower medicinal chemists.
- •Partner with medicinal chemistry teams to optimize compounds and interpret SAR.
- •Contribute to computational design discussions and translate complex modeling results into practical recommendations.
- •Requirements PhD in Computational Chemistry, Medicinal Chemistry, or related discipline.
- •Minimum of 3 years of relevant experience in pharma, biotech, or drug discovery.
- •Hands-on expertise in structure-based and ligand-based drug design methods.
- •Strong working knowledge of medicinal chemistry principles and ADME/PK concepts.
- •Practical experience with cheminformatics platforms and chemical data curation.
Required skills
PythonGit
Domain expertise
biotech
Benefits & perks
Equity incentives, Medical, dental, and vision coverage, One Medical membership, 401(k) retirement plans, Education and health/fitness incentive programs, Meditation retreats, Reading budget
Tech stack
PythonGit