Lead immunology strategy for small-molecule discovery programs, translating disease biology into evidence packages.
•Iambic Therapeutics is seeking a scientific leader with deep expertise in immunology and immunopharmacology to join the Biology group as Director or Senior Director.
•This individual will define and execute biology strategies for small-molecule discovery programs.
•Key Responsibilities Lead immunology strategy from target validation through IND-enabling studies.
•Oversee disease-relevant in vitro and ex vivo studies using primary human immune cells.
•Define and oversee in vivo efficacy, pharmacodynamic, and mechanistic studies.
•Manage and develop scientists and associates, oversee CROs and other partners.
•Requirements PhD in immunology or a related field, with 15+ years of relevant experience.
•Track record leading cross-functional small-molecule programs from hit identification through development candidate nomination.
•Deep expertise in innate and/or adaptive immunology and extensive experience with primary-cell and ex vivo studies.
•Experience designing and interpreting in vivo efficacy, pharmacodynamic, and mechanistic studies.
•Strong people leadership and executive communication skills.