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Senior Scientist, Cardiac Modeling

insitroAI-driven Drug company
South San Francisco, United StatesSenior
Andreessen Horowitz logo
Andreessen Horowitz
CPP Investments
BlackRock logo
BlackRock
ARCH Venture Partners
Third Rock Ventures
Two Sigma Ventures
Data & AI

About the role

TL;DR

Develop iPSC-derived cardiomyocyte models for cardiovascular disease research.

  • Join our cardiac disease biology team to develop iPSC-derived cardiomyocyte models for cardiovascular disease research.
  • Key Responsibilities Lead the generation and characterization of iPSC lines and their differentiation into cardiomyocytes.
  • Design and optimize iPSC-CM assays in 2D and 3D formats.
  • Build and apply isogenic iPSC-CM disease models to study cardiovascular pathophysiology.
  • Develop functional readouts of cardiomyocyte biology relevant to disease.
  • Partner with ML and computational biology teams to design experiments and interpret model outputs.
  • Requirements Ph.D. in cell biology, biomedical engineering, cardiac physiology, or a related field.
  • At least 3 years of industry experience in iPSC culture and cardiac directed differentiation.
  • Experience building and applying genetic iPSC-CM disease models.
  • Strong foundational knowledge of cardiomyocyte biology and cardiovascular disease.
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Domain expertise

biotechhealthcare

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