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insitro logo

Senior Director, Translational Medicine and Diagnostics

insitroAI-driven Drug company
South San Francisco, United States$224,000 - $299,000Director
Andreessen Horowitz logo
Andreessen Horowitz
CPP Investments
BlackRock logo
BlackRock
ARCH Venture Partners
Third Rock Ventures
Two Sigma Ventures
Data & AI

About the role

TL;DR

Lead translational medicine and diagnostics for drug discovery and development.

  • Lead translational medicine and diagnostics at insitro, driving the development of novel therapeutics for complex diseases.
  • This role offers the opportunity to significantly impact patient lives by improving clinical trial efficiency and patient outcomes through AI/ML and innovative translational strategies.
  • Key Responsibilities Build and lead insitro's translational medicine function from IND/CTA through clinical proof-of-concept.
  • Serve as translational lead for advanced pre-clinical and initial clinical-stage assets.
  • Design innovative patient stratification strategies using laboratory and digital biomarkers.
  • Collaborate closely with preclinical, clinical, regulatory, and computational teams.
  • Requirements Advanced degree in life sciences, technology, chemistry, or related discipline. 10+ years of experience in translational science, including direct experience as a translational lead delivering therapeutics and diagnostic biomarkers from FIH through proof-of-concept to NDA/BLA submission.
  • Experience applying AI/ML approaches to drug discovery and development.
  • Deep understanding of diagnostic and device regulations, GCP, clinical trial design, clinical pharmacology, biostatistics, and computation in drug development.
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Required skills

Google CloudPythonRSQL

Nice-to-have skills

TensorFlowPyTorchscikit-learnDockerKubernetesAWSGoogle CloudAzureCI/CDProject Management

Domain expertise

biotechhealthcaredeeptechai

Benefits & perks

Annual Performance Bonus Plan, Equity Incentive Plan, 401(k) plan with employer matching, Medical, dental, and vision coverage, Mental health and well-being support, Open, flexible vacation policy, Paid parental leave, Quarterly budget for books and online courses, New hire stipend for home office setup, Monthly cell phone & internet stipend, Access to free onsite baristas and daily lunch, Access to a free commuter bus network

Tech stack

PythonRSQLBashTensorFlowPyTorchscikit-learnDockerKubernetesAWSGoogle CloudAzureGitLinuxJiraConfluencePostgreSQLMySQLRedisElasticsearchDynamoDBNeo4jCI/CDGitHub ActionsJenkinsArgoCDHelmGitLab CICircleCIAnsible

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