Principal AI Scientist (Polytope Bio)
Astera InstituteAI Research, company
New York, United States$250,000 - $350,000Lead
Data & AI
About the role
TL;DR
Lead AI research for a novel bio-AI feedback loop system.
- •Astera is a private foundation focused on accelerating scientific and technological advancement.
- •Polytope Bio is a residency project at Astera building a post-training engine to connect frontier AI models with high-throughput biology, enabling new applications in generative biology.
- •Key Responsibilities Co-direct the research program, shaping scientific vision and technical execution.
- •Develop RL feedback loops to translate biological measurements into reward signals for AI models.
- •Architect model training infrastructure and build, run, and debug models.
- •Partner with the experimental team to create a cohesive biological and AI system.
- •Requirements PhD in machine learning, computational biology, or related field with 2-5 years of industry research experience post-PhD.
- •Experience training models from scratch, not just fine-tuning.
- •Hands-on experience with generative diffusion models and/or transformer architectures.
- •Deep familiarity with modern reinforcement learning methods.
Required skills
PythonTensorFlowPyTorchscikit-learn
Domain expertise
biotechdeeptechai
Benefits & perks
health insurance, company sponsored retirement plan, vision, dental
Tech stack
PythonTensorFlowPyTorchscikit-learn