Senior Scientist (In vitro / Cellular Pharmacology)
Isomorphic LabsDrug Discovery company
CambridgeSenior
Thrive Capital
GV
Temasek
CapitalG
Alphabet
MGX
Data & AI
About the role
TL;DR
Design and implement biological screening cascades for drug discovery programs.
- •Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.
- •This role is ideal for an experienced in vitro pharmacologist with significant working knowledge of biophysical, biochemical and/or cell-based functional assays, and extensive experience of providing quantitative in vitro pharmacology expertise within drug discovery projects.
- •Key Responsibilities Design efficient and comprehensive biological screening cascades for a variety of internal and partnered drug design programs.
- •Guide the optimization and implementation of biophysical and biochemical assays, including SPR, ITC, and enzymatic methodologies.
- •Direct the development and refinement of functional and phenotypic cellular assays.
- •Work with CROs to design decision-making experiments and deliver high-quality biological data.
- •Evaluate, interpret, and synthesize complex binding, kinetic, and dose-response information.
- •Requirements Ph.D. in Pharmacology, Biochemistry, Cell Biology, Biophysics, or a related scientific discipline.
- •Extensive experience in the design and implementation of biological screening cascades.
- •Deep knowledge of experimental in vitro pharmacology techniques including biophysical, biochemical and/or cellular assays.
- •Experience working with CROs in acquiring and interpreting high quality biological data.
- •Effective communication across a broad interdisciplinary team.
Required skills
PythonGraphQLREST APIOpenAPI
Nice-to-have skills
MLflowKubeflowSageMakerVertex AI
Domain expertise
biotechhealthcaredeeptechai
Tech stack
PythonGraphQLREST APIOpenAPI