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Bioinformatics Engineer, Pipelines

MithrlGenomic Data company
San Francisco, United StatesSenior
Bonfire Ventures
Jenny Fielding
Scott Hartley
Agi House
Headline logo
Headline
Obvious Ventures
Data & AI

About the role

TL;DR

Build and scale scientific processing pipelines for bioinformatics.

  • We are looking for a Lead Bioinformatics Pipeline Engineer to build and scale Mithrl’s multi modal scientific processing pipelines.
  • Key Responsibilities Design and maintain production grade bioinformatics pipelines for a wide range of data modalities.
  • Build workflows using Nextflow, nf-core modules, or similar engines with a focus on reproducibility, validation, and scalability.
  • Implement quality control, validation, and provenance tracking for all supported modalities.
  • Collaborate with the Tabular Data Team to ensure pipeline outputs map cleanly into Mithrl’s internal schemas.
  • Work with the Knowledge Curation Team to align outputs with reference genomes, annotations, and biological ontologies.
  • Requirements 6 to 8 years of experience in bioinformatics workflow engineering or computational biology.
  • Strong experience with Nextflow, nf-core, WDL, CWL, Snakemake, or similar workflow systems.
  • Proficiency in Python or R for data processing, QC, and pipeline logic.
  • Hands-on experience building pipelines for multiple biological data types.
  • Ability to design pipelines that are reproducible and containerized using Docker or Singularity.
View original posting →

Required skills

PythonRDocker

Nice-to-have skills

AWS

Domain expertise

biotech

Benefits & perks

Comprehensive PPO health coverage, 401(k)

Tech stack

PythonRDockerAWS

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